LOCUS COERULEUS ACTIVATION DURING ENVIRONMENTAL NOVELTY GATES COPYRIGHT-INDUCED LONG-TERM HYPERACTIVITY OF DOPAMINE NEURONS

Locus coeruleus activation during environmental novelty gates copyright-induced long-term hyperactivity of dopamine neurons

Summary: A key feature of the brain is the ability to handle novelty.Anything that is new will COMPLETE COLLAGEN CITRUS TWIST stimulate curiosity and trigger exploration.Novelty preference has been proposed to predict increased sensitivity to copyright.Different brain circuits are activated by novelty, but three specific brain regions are critical

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Application of Plackett-Burman Factorial Design in The Development of Curcumin Loaded Eudragit E 100 Nanoparticles

The present study was aimed to fabricate Curcumin loaded Eudragit E 100 polymeric nanoparticles and to study the effect of various manufacturing parameters on the average particle size, span, uniformity and surface area of the prepared polymeric nanoparticles by utilizing Plackett-Burman experimental designs.Curcumin loaded Eudragit E 100 nanoparti

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Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure inhibit prostate tumor growth in TRAMP mice

Dendritic cell (DC)-based vaccines pulsed with high hydrostatic pressure (HHP)-inactivated tumor cells have recently been shown to be a promising tool for prostate cancer chemoimmunotherapy.In this study, DC-based vaccines, both pulsed and unpulsed, were as effective as docetaxel (DTX) in reducing prostate tumors in the orthotopic transgenic adenoc

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